Results from a five year randomised controlled trial in Africa (Uganda and Zimbabwe), funded by the Medical Research Council and the Department for International Development, have shown that replacing routine lab tests of the safety and efficacy of HIV treatment with those based on an ongoing clinical assessment could help more children with HIV get treatment – the laboratory tests have a very low cost-benefit ratio, and omitting them would make more money available for treatment. (This is in line with the results from other studies in adults).
ARROW. The ARROW clinical trial. (2013)