Tablets are more acceptable and give fewer problems than syrups among young HIV-infected children in resource-limited settings in the ARROW trial.
- Department for International Development
- 1 January 2010
- Uganda and Zimbabwe
- Document Type:
- Conference Paper
- Cook, A., Gibb, D.M., Spyer, M., Nahirya-Ntege, P., Kekitiinwa, A. Bwakura-Dangarembizi, M.F., Kasirye, P., Bakeera-Kitaka, S., Mudzingwa, S., Nathoo, K., Byaruhanga, J., Keishanyu, R., Nabulime, G., Nankya, F., and Tezikyabbiri, J.
Of 406 HIV-infected Ugandan and Zimbabwean children aged 3 months to 17 years administered antiretroviral drugs in syrup form when enrolled in the ARROW trial during 2007-2008, 236 were switched to tablets between May 2008 and December 2009 (this was encouraged for children around 3 years of age). Questionnaires were administered to the children's carers at the time of substitution and again 8 weeks later; 186 pairs of questionniares were analysed. It was found that carers anticipated fewer difficulties using tablets than syrups, and experienced even fewer; most children and almost all carers preferred tablets.
Nahirya-Ntege, P.; Bwakura-Dangarembizi, M.F.; Byaruhanga, J.; Cook, A.; Bakeera-Kitaka, S.; Keishanyu, R.; Mudzingwa, S.; Nabulime, G.; Kekitiinwa, A.; Spyer, M.; Nankya, F.; Nathoo, K.; Tezikyabbiri, J.; Kasirye, P.; Gibb, D.M. Tablets are more acceptable and give fewer problems than syrups among young HIV-infected children in resource-limited settings in the ARROW trial. Presented at 2nd International Workshop on HIV Paediatrics, Vienna, Austria, 16-17 July 2010 and XVIII International AIDS Conference, Vienna, Austria, 18-23 July 2010. (2010)
Published: 1 January 2010
Document Type: Conference Paper
Authors: Cook, A. Gibb, D.M. Spyer, M. Nahirya-Ntege, P. Kekitiinwa, A. Bwakura-Dangarembizi, M.F. Kasirye, P. Bakeera-Kitaka, S. Mudzingwa, S. Nathoo, K. Byaruhanga, J. Keishanyu, R. Nabulime, G. Nankya, F. Tezikyabbiri, J.