People living with HIV (PLHIV) are at increased risk of tuberculosis (TB). TB is also the leading opportunistic infection contributing to about one-third of deaths in this population. The World Health Organization recommends regular screening for TB in PLHIV. Those identified to have any TB-related symptoms are investigated and treated if diagnosed with TB. We sought to evaluate outcomes of intensified case finding and factors associated with undesirable screening for TB in a large HIV programme in western Kenya.
The authors conducted a retrospective study using routine programme data from the AMPATH HIV electronic medical records database for PLHIV in care between 2015 and 2016. Screening for TB was assessed by the recorded presence of cough ≥2 weeks, fever, night sweats, unintentional weight loss, chest pain and/or breathlessness. Undesirable screening was defined as being screened in < 90% of patient clinical encounters. Data were analyzed by encounters and per-patient. Factors associated with undesirable screening were analyzed using log-binomial regression and presented as relative risks.
This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)
Owiti P, Onyango D, Momanyi R, Harries AD. Screening and testing for tuberculosis among the HIV-infected: outcomes from a large HIV programme in western Kenya. BMC Public Health. 2019;19(1):29.
Screening and testing for tuberculosis among the HIV-infected: outcomes from a large HIV programme in western Kenya