This report presents an evaluation and listing of research priorities for three insect-borne diseases – Chagas disease, human African trypanosomiasis and leishmaniasis. These diseases disproportionately afflict poor and remote populations with limited access to health services, and the pathogenic mechanisms are poorly understood but typically entail immunological processes. The work is the output of the disease reference group on Chagas disease, human African trypanosomiasis and leishmaniasis (DRG3), which was part of an independent think tank of international experts established by the Special Programme for Research and Training in Tropical Diseases (TDR) to identify key research priorities through systematic review of research evidence and input from stakeholder consultations.
TDR Disease Reference Group on Chagas Disease, Human African Trypanosomiasis and Leishmaniasis. Research Priorities for Chagas Disease, Human African Trypanosomiasis and Leishmaniasis. World Health Organization, Geneva, Switzerland (2012) 116 pp. ISBN 978 92 4 120975 5 [WHO Technical Report Series No. 975]