Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy

This is a systematic review and meta-analysis

Abstract

Oral nifedipine is recommended along with labetalol and hydralazine for treatment of severe hypertension during pregnancy by most authorities. Although nifedipine is cheap and easily administered, the usage pattern among health care providers suggests a strong preference for labetalol despite lack of evidence for the same.

This study aims to determine the efficacy and safety of oral nifedipine for treatment of severe hypertension of pregnancy compared with intravenous labetalol.

This research is supported by the Department for International Development’s Evidence Building and Synthesis Research Programme which is led by Liverpool School of Tropical Medicine

Citation

S Shekhar, N Gupta, R Kirubakaran, P Pareek. Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. BJOG: An International Journal of Obstetrics & Gynaecology 123:40–47 DOI: 10.1111/1471-0528.13463

Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis

Published 25 June 2015