Microbicides Development Program, Tanzania-Baseline Characteristics of an Occupational Cohort and Reattendance at 3 Months.
- Department for International Development
- Document Type:
- Journal Article
- Gavyole, A., Watson-Jones, D., Changalucha, J., Balira, R., Hayes, R.J. Everett, D., Ross, D.A., Chirwa, T., Vallely, A., Kasindi, S., Knight, L., Hambleton, I.R., Moyes, J., and Pujades-Rodriguez, M.
Objectives: To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated with reattendance at 3 months, in preparation for a microbicide trial. Study Design: 1573 women aged 16-54 years working in food outlets and recreational facilities were enrolled, interviewed, and examined at community-based reproductive health clinics, provided specimens for HIV/STI and pregnancy testing, and attended 3 monthly clinical follow-up. Results: Baseline prevalences were as follows: HIV 25.5%; pregnancy 9.7%; herpes simplex virus type-2 74.6%; active syphilis 10.2%, bacterial vaginosis 52.6%; gonorrhea 5.5%; chlamydia 5.9%; and trichomoniasis 12.3%. Reattendance at 3 months was 74.1% and was higher in older women, less mobile women, and in those who received an HIV-negative result at enrollment. Conclusions: Baseline characteristics of this occupational group suggest their suitability for microbicide trials. A screening round, locally appropriate informed consent procedures, and effective community tracing may help reduce losses to follow-up in such settings.
Sexually Transmitted Diseases (2007) 34 (9) 638-643 [doi:10.1097/OLQ.0b013e3180325120]
Document Type: Journal Article
Authors: Gavyole, A. Watson-Jones, D. Changalucha, J. Balira, R. Hayes, R.J. Everett, D. Ross, D.A. Chirwa, T. Vallely, A. Kasindi, S. Knight, L. Hambleton, I.R. Moyes, J. Pujades-Rodriguez, M.