This multi-agency report, led by MSH, with input from CHAI, FIND, MMV,
JSI/Deliver, PMI, RBM, WDI and WHO provides guidance for the specific
interaction between artemisinin-based combination therapies (ACTs) and
rapid diagnostic tests (RDTs). It shows users how to develop a stepwise
approach to quantifying ACT and RDT demand at the program level and to
understand the data and the assumptions that are needed for
quantification, especially when the data are imperfect.
Specifically, the manual illustrates how to plan, forecast, and ensure
supplies of ACTs and RDTs through the following steps:
- Identify the data needed and where the data comes from.
- Choose the appropriate method for forecasting based on the data
- Identify, obtain consensus on, and apply assumptions that may be
needed for quantification included those for missing data.
- Estimate the effect of any programmatic factors (e.g., scale-up) or
environmental factors (e.g., seasonality of malaria) that may influence
- Identify the unique characteristics of malaria, ACTs, and RDTs, and
special considerations to be applied in their quantification.
- Use the forecasting data and assumptions to calculate the quantities
needed for the specific quantification period.
- Interpret the estimates obtained.
- Develop supply schedules to ensure that an uninterrupted supply of
ACTs and RDTs is available, and apply practical steps on how to develop
and manage changing needs to avoid over- or underestimating future
needs, thereby minimizing shortages or wastage.
Shretta, R. Manual for quantification of malaria commodities. Rapid Diagnostic Tests and Artemisinin-Based Combination Therapy for First-Line Treatment of Plasmodium Falciparum Malaria. Strengthening Pharmaceutical Systems Program. Management Sciences for Health, Arlington, VA, USA (2011) 116 pp.
Manual for quantification of malaria commodities. Rapid Diagnostic Tests and Artemisinin-Based Combination Therapy for First-Line Treatment of Plasmodium Falciparum Malaria.