Linezolid-associated optic neuropathy in drug-resistant tuberculosis patients in Mumbai, India
Patients on linezolid-containing drug-resistant TB (DR-TB) regimen often develop adverse-events
Abstract
This study was a retrospective cohort study using routine clinical and laboratory data in Médecins Sans Frontières (MSF) HIV/DR-TB clinic in collaboration with Lilavati Hospital & Research Center, Mumbai, India. All DR-TB patients on linezolid-containing treatment regimens were included in the study and underwent routine evaluations for systemic and/or ocular complaints. Ophthalmological evaluation by a consultant ophthalmologist included visual-acuity screening, slit-lamp examination and dilated fundus examination.
This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)
Citation
Mehta S, Das M, Laxmeshwar C, Jonckheere S, Thi SS, Isaakidis P (2016) LinezolidAssociatedOptic Neuropathy in Drug-Resistant Tuberculosis Patients in Mumbai, India. PLoS ONE 11(9): e0162138.
Links
Linezolid-associated optic neuropathy in drug-resistant tuberculosis patients in Mumbai, India