Isolation of Mycobacterium bovis from human cases of cervical adenitis in Tanzania: a cause for concern?

Abstract

SETTING: Pastoralist communities in the Northern and Southern zones of Tanzania.

DESIGN: Observational study.

OBJECTIVES: To determine the involvement of Mycobacterium bovis in tuberculosis cases presenting at tuberculosis (TB) clinics in rural areas in these zones.

METHODS: A total of 149 tuberculosis cases identified on the bases of clinical manifestation were sampled. Appropriate specimens were cultured on two Löweinstein Jensen slants with respectively glycerol and pyruvate added. Forty-one isolates were cultured and subjected to biochemical typing.

RESULTS: Overall, 31 (70.5%) of the mycobacterial isolates recovered from all forms of tuberculosis were identified as M. tuberculosis, seven (16.0%) were identified as M. bovis, and six (13.6%) were other mycobacterial species. There was a significantly higher isolation rate (P
CONCLUSION: Based on these findings, it is imperative that M. bovis be considered as a pathogen of concern to people living in rural areas of Tanzania. Further work is required to establish a zoonotic link between cattle and the people in these communities who rear them.

Citation

Kazwala, R.R.; Daborn, C.; Sharp, J.M.; Kambarage, D.;M. Jiwa, S.F.H.; Mbembati, N.A. Isolation of Mycobacterium bovis from human cases of cervical adenitis in Tanzania: a cause for concern? International Journal of Tuberculosis and Lung Disease (2001) 5 (18) 87-91.

Isolation of Mycobacterium bovis from human cases of cervical adenitis in Tanzania: a cause for concern?

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