Is artesunate better than quinine for treating severe malaria? Evidence Update, Malaria Series, August 2008.
Each Evidence Update is a 2-page summary of a Cochrane Review of healthcare interventions relevant to people in low-income and middle-income countries.
This Evidence Update is adapted from Jones KL, Donegan S, Lalloo DG. Artesunate versus quinine for treating severe malaria. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No.: CD005967.
For adults with severe malaria, intravenous artesunate results in fewer deaths and fewer cases of hypoglycaemia than quinine. There is insufficient evidence to make firm conclusions about the treatment of children or the effectiveness of intramuscular artesunate.
Effective Health Care Research Programme Consortium, Liverpool School of Tropical Medicine, Liverpool, UK, 2 pp.