Improved growth and anaemia in HIV-infected African children taking cotrimoxazole prophylaxis

Abstract

The impact of cotrimoxazole (CTX) on growth and/or anemia was investigated in 541 human immunodeficiency virus-infected, antiretroviral therapy–naive Zambian children enrolled in the Children with HIV Antibiotic Prophylaxis trial. Compared with children randomized to receive placebo, children randomized to receive CTX had slower decreases in weight-for-age (P  =  .04) and height-for-age (P  =  .01), and greater increase in hemoglobin level (P  =  .01). These findings argue for expanded early CTX use.

Citation

Prendergast, A.; Walker, A.S.; Mulenga, V.; Chintu, C.; Gibb, D.M. Improved Growth and Anemia in HIV-Infected African Children Taking Cotrimoxazole Prophylaxis. Clinical Infectious Diseases (2011) 52 (7) 953-956. [DOI: 10.1093/cid/cir029]

Improved growth and anaemia in HIV-infected African children taking cotrimoxazole prophylaxis

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