Impact of rapid molecular diagnostic tests on time to treatment initiation and outcomes in patients with multidrug-resistant tuberculosis, Tamil Nadu, India

India is replacing culture and drug sensitivity testing (CDST) with rapid molecular tests for diagnosing MDR-TB

From:
Department for International Development
Published
1 October 2016
Country:
India
Document Type:
Journal Article
Theme:
Health
Authors:
Nair, D, Navneethapandian, Pooranaganga N, Tripath, J.P., Harries, A.D

Abstract

Cohort study involving MDR-TB patients from 6 districts in Tamil Nadu state, who underwent CDST (2010-2011) and rapid tests (2012-2013). This paper concludes that rapid molecular diagnostic tests shortened the time to initiate treatment which was associated with reduced unfavourable outcomes in MDR-TB patients. This supported the policy to scale up these tests in India.

This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)

Citation

Dina Nair, Pooranaganga D. Navneethapandian, Jaya Prasad Tripath, Anthony D. Harries et all (2016) Impact of rapid molecular diagnostic tests on time to treatment initiation and outcomes in patients with multidrug-resistant tuberculosis, Tamil Nadu, India, Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 110, Issue 9, 11 October 2016, Pages 534–541.

Impact of rapid molecular diagnostic tests on time to treatment initiation and outcomes in patients with multidrug-resistant tuberculosis, Tamil Nadu, India Subscription or payment maybe required to access

Published 1 October 2016
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