The TB Alliance is developing a TB drug database as a resource for the TB drug research community. The materials published in this issue of Tuberculosis represent initial efforts towards this goal. The aim is to bring together information on all approved drugs used to treat tuberculosis, on drugs in clinical development for TB, and on some approved drugs being investigated for potential use in TB such as thioridazine. A total of 27 drugs are included in the current version of the database. Referenced data include physical characteristics, basic biology, efficacy and safety in humans, and absorption, distribution, metabolism and excretion (ADME). The database is designed to be an overview of TB drug information rather than an in-depth comprehensive review of all aspects of TB treatment.
Global Alliance for TB Drug Development. Handbook of Anti-Tuberculosis Agents. Tuberculosis (2008) 88 (2) 85-169.