This document (available in English and French) defines general principles to be used in implementing clinical research, subject to adaptation to suit local circumstances or improvements in the light of experience; it gives specific details where possible. The subjects covered are: community engagement; informed consent; risk reduction counselling and provision of condoms; referral for individuals who test HIV-positive at pre-enrolment screening; sexually transmitted infection screening and treatment; provision of antiretrovirals for participants; services for study staff; treatment and compensation for physical harm; and post-trial access to microbicides. [See also Guidelines for conducting IPM clinical trials (2nd edition)].
International Partnership for Microbicides. Guidelines for the conduct of IPM’s clinical trials. (2006) 8 pp.