Guidance Framework for testing genetically modified mosquitoes

Abstract

Genetically modified mosquitoes (GMM) engineered to be incapable of transmitting certain pathogens or able to reduce populations of similar native mosquito vectors have emerged as a promising new tool to combat vector-borne diseases like malaria and dengue. This guidance framework aims to foster quality and consistency among processes for testing and regulating new genetic technologies by proposing standards of efficacy and safety testing comparable to those used for trials of other new public health tools. It does not represent the views of the World Health Organization (WHO) or the Foundation for the National Institutes of Health (FNIH) which jointly commissioned it, or provide recommendations on what to do. Rather, it is a document that brings together what is known, based on current research evidence, about how best to evaluate GMM.

Citation

TDR. Guidance Framework for testing genetically modified mosquitoes. TDR/World Health Organization, Geneva, Switzerland (2014) xxv + 132 pp. ISBN 978 92 4 150748 6

Guidance Framework for testing genetically modified mosquitoes

Help us improve GOV.UK

Don’t include personal or financial information like your National Insurance number or credit card details.