Reports on a large multicenter genome-wide association study of Plasmodium falciparum resistance to artemisinin
The study took place across 15 locations in Southeast Asia. Its findings indicate that the risk of new resistance-causing mutations emerging is determined by specific genetic factors in the parasite population.
Miotto, O., et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nature Genetics (2015) 47, 226–234 pp.