Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa

Abstract

The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings.

Citation

Muyoyeta, M.; Mueller, D.H.; van Helden, P.D.; Mwenge, L.; Schaap, A.; Kruger, C.; Gey van Pittius, N.C.; Lawrence, K.; Beyers, N.; Godfrey-Faussett, P.; Ayles, H.; de Haas, P.E.W. Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa. Journal of Clinical Microbiology (2010) 48 (10) 3773-3775. [DOI: 10.1128/JCM.01688-09]

Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa

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