At the end of 2005, about 40 million people worldwide were living with HIV/AIDS, most of them adults and 95 percent of them living in developing countries. Although vigorous prevention programs are under way in many countries, about 3 million people still died from AIDS in 2005 and more than 13,000 people became infected with HIV every day. Hence there is an urgent need for stronger and more effective HIV prevention. New technologies are required to augment existing prevention methods. An HIV vaccine could make an enormous difference in the effort to reverse the pandemic, thereby saving tens of millions of lives.
PLoS Med 3(10): e398. [doi:10.1371/journal.pmed.0030398]