The objectives of the study reported in this conference poster were to estimate the incidence of malaria in relation to time on antiretroviral therapy (ART), and to assess the association between malaria and baseline CD4 count, WHO clinical stage, haemoglobin, body mass index, age, education, gender and use of cotrimoxazole. The incidence of malaria and its potential risk factors were assessed in a cohort of HIV-infected ugandans on cART, who were enrolled in the DART trial. The methods and results are briefly presented. It was found that initiation of cART, with recovery of the immune system results in a reduction in the rates of malaria. Concurrent use of cotrimoxazole prophylaxis is protective against malaria. At very low CD4 counts (3) there is an increased risk of malaria. A higher level of education was associated with a lower risk of malaria.
Kasirye, R.; Levin, J.; Munderi, P.; Okell, L.; Walker, S.; Mugisha, A.; Grosskurth, H. Epidemiology of malaria in HIV infected patients on ART in Uganda: a prospective cohort study. Presented at the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention, Cape Town, South Africa, 19-22 July 2009. (2009) 1 pp.