There are approximately 13000 cases of multi drug resistant Tuberculosis (MDRTB) diagnosed in Pakistan each year. Treatment of MDR-TB requires 18-24 months of medication, support and supervision at a significant cost. The study will assess 2 types of service delivery models for their effectiveness and cost-effectiveness in low resource settings in Pakistan. These care models are:
- community-based care (early discharge to peripheral care)
- hospital-based care (late discharge to peripheral care)
The primary objective is to determine the difference between the proportions of MDR-TB patients successfully treated using community-based care, compared to patients treated using hospital-based care. Secondary objectives include comparing the intermediate outcome (smear and culture conversion rate), the costs to the patients and health services, and the social feasibility of implementation for each method.
COMDIS. Effectiveness and feasibility of hospital and community-based delivery of care for multi-drug resistant tuberculosis in Pakistan. (2014)