SETTING: Primary health care centres in Callao, Peru.
OBJECTIVES: To evaluate the effect of universal access to the
microscopic-observation drug susceptibility (MODS) assay on treatment
outcomes in new and primary multidrug-resistant tuberculosis (MDR-TB)
patients and on the process of drug susceptibility testing (DST).
DESIGN: Retrospective review of tuberculosis (TB) registers and clinical
records before (2007) and after (2009) the introduction of MODS in 2008.
RESULTS: There were 281 patients in each cohort. Favourable treatment
outcomes for 2007 (81%) and 2009 (77%) cohorts were similar. There was
an increase in loss to follow-up (from 6% to 10%, P
CONCLUSION: Universal access to MODS increased DST coverage, reduced the
time required to obtain DST results and was associated with reduced
failure rates. MODS can make an important contribution to TB management
and control in Peru.
Mendoza-Ticona, A.; Alarcon, E.; Alarcon, V.; Bissell, K.; Castillo, E.; Sabogal, I.; Mora, J.; Moore, D.; Harries, AD. Effect of universal MODS access on pulmonary tuberculosis treatment outcomes in new patients in Peru. Public Health Action (2012) 2 (4) 162-167. [DOI: 10.5588/pha.12.0033]
Effect of universal MODS access on pulmonary tuberculosis treatment outcomes in new patients in Peru.