Do pre-erythrocytic vaccines prevent malaria illness and infection? Evidence Update, Malaria Series, February 2008.
Each Evidence Update is a 2-page summary of a Cochrane Review of healthcare interventions relevant to people in low-income and middle-income countries.
This Evidence Update is adapted from Graves P, Gelband H. Vaccines for preventing malaria (pre-erythrocytic). Cochrane Database of Systematic Reviews 2006, Issue 4. Art. No.: CD006198.
One vaccine (RTS,S) shows promise, but further trials are needed to confirm the benefits. There is not enough evidence to assess the effectiveness of three other pre-erythrocytic vaccines.
Effective Health Care Research Programme Consortium, Liverpool School of Tropical Medicine, Liverpool, UK, 2 pp.