Do drugs that aim to reduce the dehydration of red blood cells prevent crises in people with sickle cell disease? Evidence Update, Sickle Cell Disease Series, March 2008.
Each Evidence Update is a 2-page summary of a Cochrane Review of healthcare interventions relevant to people in low-income and middle-income countries.
This Evidence Update is adapted from Singh PC, Ballas SK. Drugs for preventing red blood cell dehydration in people with sickle cell disease. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No.: CD003426.
Zinc sulfate appears promising for preventing sickle cell crises, but there is not enough evidence to recommend its use.
Effective Health Care Research Programme Consortium, Liverpool School of Tropical Medicine, Liverpool, UK, 2 pp.