In people with tuberculosis direct observation of treatment yielded similar cure and treatment completion rates as self-administration of treatment.People with tuberculosis need to take drugs for at least six months. Many do not complete their treatment course, and for this reason services for patients with tuberculosis often use different approaches to encourage people to complete their treatments. This review found no evidence that direct observation compared to self-administered treatment improved treatment adherence and outcomes.
The Cochrane Database of Systematic Reviews 2003, Issue 1. Art. No.: CD003343. DOI: 10.1002/14651858.CD003343.