The approach used for the study was based on a rapid appraisal of the
literature and use of research tools, expert opinion and workshops to
identify priorities for research into interventions for control of
zoonoses in low and middle income countries (LMICs). The analysis was
based on detailed studies of 20 zoonotic diseases, selected for their
development relevance and to be representative of the diversity of
For each of 20 selected zoonoses, literature reviews and expert
interviews were undertaken to identify opportunities for innovative
technologies and management practices for control of zoonoses, focused
primarily but not exclusively on Asia and Africa. Diagnostics, drugs,
vaccines and management practices for each selected disease were
Sections 1 and 2 of the report cover the study methodology and zoonotic
disease selection. Section 3 considers the complex agricultural and
health dimensions of zoonotic diseases and their impact in a development
context. Then Section 4 considers the drivers which will influence the
selection of interventions for research, including biological,
socio-economic and cultural factors. A protocol is suggested for
selecting interventions, based on these factors and its application to
the 20 selected diseases is examined. Cross-cutting analyses drawing
case studies from these diseases are examined identifying patterns of
successful control, cross-cutting gaps and opportunities for research.
In the following sections, we examine prioritization from the different
perspective of interventions, considering diagnostics (Section 5), drugs
(Section 6) and vaccines (section 7) and how these technologies can be
used effectively for integrated control.
tKock, R.; Croft, S.; Dixon, M.; Fletcher, C.; Good, L.; Guzman, J.; Heymann, D.; Liyanage, R.; McKeever, D.; McNerney, R.; Peeling, R.; Moran, M.; Pfeiffer, D.; Waage, J.; Wu, L. DFID Zoonoses Report 6. Prioritising the need for new diagnostics, medicine, vaccines and management practices of zoonoses which have significant impact in the developing world. Royal Veterinary College, Hatfield, UK (2012) 126 pp.
DFID Zoonoses Report 6. Prioritising the need for new diagnostics, medicine, vaccines and management practices of zoonoses which have significant impact in the developing world.