Tuberculous pleural effusion results from tuberculous infection of the membrane covering of the lungs. This results in a build up of fluid around the lung that impairs breathing and may lead to restriction of lung function in the long term. Some clinicians believe that corticosteroids used in combination with antituberculous drugs can help to prevent these complications. We found no clear evidence supporting the use of corticosteroids in people with tuberculous pleural effusion, regardless of HIV status. However, only one trial evaluated the balance between benefit and harm of corticosteroids in people infected with HIV.
Engel, M.E.; Matchaba, P.T.; Volmink, J. Corticosteroids for tuberculous pleurisy. Cochrane Database of Systematic Reviews (2007) (Issue 4) Art. No.: CD001876. [DOI: 10.1002/14651858.CD001876.pub2]