Comparison between calculated and direct measurements of CD4 percentage for immunological monitoring of antiretroviral therapy in children.

From:
Department for International Development
Published
1 January 2010
Country:
Uganda
Document Type:
Research Paper
Theme:
Health
Authors:
Hughes, P., Munderi, P., Levin, J., Kihembo, M., Ntege, N.P., Muhangi, M., Tweyongyere, R.

Abstract

Among 99 children enrolled in the ARROW trial of anti-HIV therapy, the percantage of CD4 lymphocytes among total lymphocytes was measured directly using one type of machine, and calculated from the absolute numbers of CD4 lymphocytes and total lymphocytes measured using two different machines. The latter method showed strong agreement with the former; it is concluded that it could be a reliable alternative method for paediatric immunologic monitoring in centres that can afford low cost CD4 count testing facilities but do not have access to automated analysers.

Citation

Presentation from 4th National Paediatric HIV/AIDS conference, Kampala, Uganda, 28-30 September 2010.

Comparison between calculated and direct measurements of CD4 percentage for immunological monitoring of antiretroviral therapy in children.

Published 1 January 2010
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