Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I IFNs are identified, however, only limited data is available on the repertoire of IFNs in avian species. Here we report the characterization of chicken IFN-κ (chIFN-κ) near the type I IFN locus on the sex-determining Z chromosome.
This work arises from the Zoonoses and Emerging Livestock Systems (ZELS) programme.
Santhakumar D, Iqbal M, Nair V, Munir M. (2017). Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities. Sci Rep. 7(1): 2719
Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities