CD4 response to ART in previously untreated adults with HIV infection in Africa: the DART trial.

Abstract

As part of a trial comparing monitoring strategies (and investigating the possible) benefits of structured treatment interruptions) in symptomatic HIV-infected patients in Uganda and Zimbabwe, CD4 lymophocyte numbers at baseline and after 24 weeks of treatment with zidovudine, lamivudine and tenofovir (switching from zidovudine to stavudine in a few cases) were investigated in 474 patients. Increases in CD4 lymphocyte counts with treatment were found to be independent of baseline count, age, sex, weight, disease stage and almost all other factors studied, and were comparable with those found in industrialized countries.

Citation

11th Conference on Retroviruses and Opportunistic Infections, San Francisco, USA, 8-11 February 2004: Abstract 592.

CD4 response to ART in previously untreated adults with HIV infection in Africa: the DART trial.

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