In Uganda there about 1.2 million deliveries without Prevention of Mother To Child Transmission (PMTCT) interventions annually. About 30,000 infants become HIV infected each year, and because of limited infant diagnosis and treatment, about half of them die before their 2nd birthday.
The Medical Research Council in Uganda at its rural site in Kyamulibwa sub-county, has been conducting epidemiological studies since 1989 on a general population cohort (GPC). Clinical research in adults and children has been carried out since 1990 and 2002 respectively.
Pregnant women identified through the annual sero surveys in the GPC, local council vital recorders and antenatal clinics at local health centres, were counselled to have an HIV test. HIV positive women were counselled on PMTCT and those who gave informed consent were offered a comprehensive package of interventions which included antenatal care, ARVs for PMTCT or ART for those with CD4 counts
Munyagwa, M. Adherence to prevention of mother to child transmission of HIV interventions: results from operational research. Evidence For Action Case Study No. 12 June (2011) , 2pp