Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A

A community-based, randomised placebo-controlled trial

Abstract

Biofortification is a strategy to relieve vitamin A (VA) deficiency. Biofortified maize contains enhanced provitamin A concentrations and has been bioefficacious in animal studies and a small number of human studies.

The study sought to determine changes in total body reserves (TBRs) of vitamin A with consumption of biofortified maize.

Citation

Gannon, B.; Kaliwile, C.; Arscott, S.A.; Schmaelzle, S.; Chileshe, J.; Kalungwana, N.; Mosonda, M.; Pixley, K.; Masi, C.; Tanumihardjo, S.A. Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial. American Journal of Clinical Nutrition (2014) 100 (6) 1541-1550. [DOI: 10.3945/ajcn.114.087379]

Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial

Published 1 January 2014