A high proportion of children with persistent diarrhoea in middle and low income countries die. The best treatment is not clear. The authors conducted a systematic review to evaluate the effectiveness of antimicrobial drug treatment for persistent diarrhoea of unknown or non-specific cause. The conclusion was that there is little evidence as to whether or not antimicrobials help treat persistent diarrhoea in young children in low and middle income countries.
Abba, K.; Sinfield, R.; Hart, C.; Garner, P. Antimicrobial drugs for persistent diarrhoea of unknown or non-specific cause in children under six in low and middle income countries: systematic review of randomized controlled trials. BMC Infectious Diseases (2009) 9 (1) 24. [DOI: 10.1186/1471-2334-9-24]