The objective of this study was to consider the use of statistical methods that aim to prioritize the updating of a collection of systematic reviews based on preliminary literature searches. A new simulation-based method estimating statistical power and the ratio of the weights assigned to the predicted new and old evidence, and the existing Barrowman n approach is considered. Using only information on the numbers of subjects randomized in the “new” trials, these were applied retrospectively, by removing recent studies, to existing systematic reviews from the Cochrane Infectious Diseases Group.
Journal of Clinical Epidemiology, 2009, 62, (3), pp. 241-51.