A preventive AIDS vaccine, even one that is only partially effective, could have a tremendous impact on the number of new HIV infections in low- and middle-income countries. Each infection prevented by an AIDS vaccine would reduce the number of individuals who would eventually require a life-long regimen of antiretroviral treatment (ART). Modeling the potential impact of an AIDS vaccine demonstrates the number of new infections that a vaccine could prevent, which provides a basis for calculating the potential cost-savings that a vaccine could generate by reducing the number of additional people requiring ART.
International AIDS Vaccine Initiative (IAVI). AIDS Vaccines: Exploring the Potential Cost/Benefit. International AIDS Vaccine Initiative (IAVI), New York, USA (2012) 4 pp. [IAVI Insights - Policy Brief 30]