Smear diagnosis of pulmonary tuberculosis (PTB) requires three sputum examinations over 2 days. We evaluated the performance of two sputum specimens obtained on a single day (the second specimen submitted 1 h after the first) against the standard 2-day method in rural Ethiopia. A total of 243 suspects were enrolled; 52 had confirmed PTB: 49 (94%) were detected by the same-day method and 51 (98%) by the standard method (P > 0.5). The same-day approach would reduce the number of visits required for diagnosis, save resources for the health system and the patient, and ultimately improve case detection in poorer countries.
Cambanis, A.; Yassin, M.A.; Ramsay, A.; Squire, S.B.; Arbide, I.; Cuevas, L.E. A one-day method for the diagnosis of pulmonary tuberculosis in rural Ethiopia. International Journal of Tuberculosis and Lung Disease (2006) 10 (27) 230-232.