A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations

18 men participated in a 6-week controlled consumption study of a low-zinc, rice-based diet

Abstract

Food fortification has been recommended to improve a population’s micronutrient status. Biofortification techniques modestly elevate the zinc content of cereals, but few studies have reported a positive impact on functional indicators of zinc status.

The authors determined the impact of a modest increase in dietary zinc that was similar to that provided by biofortification programs on whole-body and cellular indicators of zinc status. 18 men participated in a 6-week controlled consumption study of a low-zinc, rice-based diet.

This work is an output of the HarvestPlus Programme. The Department for International Development is one of the main donors for HarvestPlus.

Citation

Zyba, Sarah J., Swapna V. Shenvi, David W. Killilea, Tai C. Holland, Elijah Kim, Adrian Moy, Barbara Sutherland, Virginia Gildengorin, Mark K. Shigenaga, and Janet C. King. 2017. A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations. The American Journal of Clinical Nutrition 105 (2): 343-351. https://doi.org/10.3945/ajcn.116.135327.

A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations

Published 1 February 2017