Research and analysis
Table 2a: Effects on IQ/Cognitive Effects
Updated 7 January 2021
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| IQ/ Cognitive Effects |
|---|
| Meta-analyses |
| Veroniki et al 2017b |
| Cognitive Developmental Delay |
| Bromley et al 2014 |
| IQ mean (SD) |
| Verbal IQ (VIQ) |
| Performance IQ (PIQ) |
| Banach et al 2010 |
| Wechsler Scale PIQ |
| Bayley or McCarthy scale FSIQ |
| Pregnancy Registries |
| Gopinath et al. 2015 |
| Wechsler scale |
| Full Scale IQ |
| Mean (SD) |
| Huber-Mollema et a l2020 |
| Wechsler Intelligence Scale |
| Full-Scale IQ (FSIQ) |
| Verbal IQ (VIQ) |
| Performance IQ (PIQ) |
| Processing Speed Index |
| Mean (SD) |
| Individual AED |
| Vs |
| VPA |
| Kerala Pregnancy Registry |
| Thomas et al 2007 |
| Full Scale IQ (FSIQ- adaptation of Wechsler Intelligence Scale) |
| Malayalam Language Test (MLT) – local proficiency test for language |
| vs |
| Age Matched Controls |
| Prospective studies |
| Cohen et al 2019 |
| Standardised mean of 6 years IQ (95% CI) |
| Attention/concentration |
| Verbal immediate |
| Verbal delayed |
| Delayed recognition |
| Visual immediate |
| Visual delayed |
| Learning |
| Titze et al 2008 |
| Wechsler Adult Intelligence Scale |
| (WAIS) |
| Scolnik et al 1994 |
| Global IQ |
| (Bayley or McCarthy Scale) |
| Mean (SE) |
| AED |
| Vs |
| Control |
| Others |
| Reinisch et al 1995 |
| Retrospective cohort study |
| Denmark |
| Wechsler Adult Intelligence Scale |
| (WAIS) |
| Verbal IQ (VIQ) |
| Mean (SD) |
| Danish Military Board Intelligence Test BPP scores |
| (IBPP) |
| Hanson et al 1976 |
| WISC full scale IQ at 7 years |
| Mean (SD) |
| Rihtman et al |
| Israeli Teratogen Information Service |
| IQ tests |