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The indication for the treatment of post-operative pain has been removed from the licences of all prolonged release opioids due to the increased risk of persistent post-operative opioid use (PPOU) and opioid-induced ventilatory impairment (OIVI).
Updated product information and packaging will help patients better understand the risks of dependency, addiction, and withdrawal with these medicines.
Insufficient pain management is common in disaster settings, and regional anesthesia has the potential to reduce pain in injured patients
There are currently 2 recognised viruses that cause haemorrhagic fever illnesses in Bolivia that are classed as high consequence infectious diseases (HCIDs). These are Machupo virus (MACV) and Chapare virus (CHAPV).
Change to the information provided on adverse events in the Summary of Product Characteristics (SPC).
Safety leaflet on opioid medicines to help patients and their families reduce the risks of harm.
Public Assessment Report on the removal of the indication for post-operative pain for modified-release opioids.
Study protocol for a randomized controlled trial in Regional Anesthesia Techniques for a Planned Randomized Controlled Trial in a Disaster Setting
These reports explain our assessment of the scientific evidence used to lead to regulatory decisions on the safety of medicines or medicines classes.
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