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Some batches of gentamicin sulphate active pharmaceutical ingredient (API) used to manufacture gentamicin may contain higher than expected levels of histamine, which is a residual from the manufacturing process. Monitor patients for signs of histamine-related adverse reactions.
Evidence suggests an increased risk of aminoglycoside-associated ototoxicity in patients with mitochondrial mutations, including cases in which the patient’s aminoglycoside serum levels were within the recommended range. These mitochondrial mutations are rare and penetrance is uncertain. Genetic testing should not...
Caution in Use: Distribute to Hospital Pharmacy, Ward and Operating Theatre Level
Implications for empiric antimicrobial therapy.
Details of certificates issued under the Special Import System for the top ten veterinary medicines imported 1 October to 31 December 2025.
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