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A weekly digest of health protection related news and surveillance reports from Public Health England.
Dstl funds research into gut health which could improve the operational effectiveness of troops deployed overseas.
Decreased vitamin B12 levels, or vitamin B12 deficiency, is now considered to be a common side effect in patients on metformin treatment, especially in those receiving a higher dose or longer treatment duration and in those with existing risk factors....
We remind healthcare professionals that elderly patients are at an increased risk of adverse neurological and cardiac effects when being treated with haloperidol for delirium. The lowest possible dose of haloperidol should be used for the shortest possible time, and...
Employment Tribunal decision.
Use baricitinib with caution in patients with diverticular disease and in those concomitantly treated with medications associated with an increased risk of diverticulitis.
People who take stimulant laxatives for constipation are being advised that these will now be sold in smaller packs, with on-pack warnings.
If constipation occurs during treatment with clozapine (Clozaril, Denzapine, Zaponex), it is vital that it is recognised and actively treated.
New recommendations following a recent clinical trial which found that in patients with type 1 hepatorenal syndrome terlipressin may cause serious or fatal respiratory failure at a frequency higher than previously known, and that terlipressin increases the risk of sepsis...
Use trametinib, authorised either as monotherapy or combined with dabrafenib, with caution in patients with risk factors for gastrointestinal perforation.
PHE is issuing advice to people travelling to Egypt after a number of people, including children, have returned with a serious illness caused by E. coli infection.
PHE raising awareness of Shigella infection risk among gay and bisexual men in England.
Prescribing advice should be followed carefully, particularly recommended upper dose limits due to associated higher gastrointestinal risk than most other NSAIDs in the class.
Patients on ipilimumab who present with diarrhoea or other symptoms of colitis, and those who do not respond to steroid treatment for immune-related colitis, should be investigated to exclude other causes, including infections such as cytomegalovirus (CMV). There have been...
UK Health Security Agency (UKHSA) data released shows a sharp increase in reports of confirmed cases of norovirus – the most common infectious cause of vomiting and diarrhoea.
New research reveals only 1 in 2 people (55%) would visit their doctor if they had heartburn most days for 3 weeks or more.
Cases of pancreatitis, with or without sphincter of Oddi spasm, have been reported in patients taking eluxadoline. Some cases have resulted in hospitalisation and death, primarily in patients who have undergone cholecystectomy.
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