Membership

Membership and minutes for the Commission on Human Medicines and its expert advisory groups.

The Secretary of State for Health and Social Care is looking to appoint one lay and two specialist Commissioners to the Commission on Human Medicines (CHM).

We are looking for skilled communicators with the ability to operate effectively on a national expert scientific committee.

For more information please visit the Centre for Public Appointments.

The Chair and Commissioners are appointed in accordance with the Code of Practice for Ministerial Appointments to Public Bodies, issued by the Commissioner for Public Appointments. The Chair and Commissioners follow a code of practice, in which they are precluded from holding personal interests. Their interests in the pharmaceutical industry are published in the Commission’s annual report each year.

The Commission meets monthly in London. The Commission is supported in its work by Expert Advisory Groups (EAGs), covering various areas of medicine. In addition, the Commission calls on experts not readily available through its membership.

Members and chair

Professor Stuart Ralston MB ChB MD FRCP FMedSci FRSE FFPM (Hon): Arthritis Research UK Professor of Rheumatology, University of Edinburgh, Western General Hospital, Edinburgh (Chair)

Dr J Colin Forfar BSc (Hons) MBChB PhD MD MA FRCP FRCP (Edin): Consultant Physician and Cardiologist, John Radcliffe Hospital, Oxford

Dr Jamie Fraser BSc MB ChB MRCGP GP Partner, Southside Surgery, Inverness

Professor Jonathan S Friedland MA PhD FRCP FRCPE FRCPI FECCMID FMedSci: Deputy Prinicipal, St. George’s University of London: Hon Consultant in Infectious Diseases St George’s University Hospitals NHS Foundation Trust

Dr Richard Gilson MD FRCP: Director, Centre for Sexual Health & HIV Research and Head, Research Department of Infection and Population Health, University College London

Professor Martin Gore CBE MBBS PhD FRCP: Medical Director and Consultant Medical Oncologist, The Royal Marsden NHS Foundation Trust and Professor of Cancer Medicine Institute of Cancer Research

Professor Malcolm R Macleod BSc MBChB MRCP PhD FRCP (Edin): Professor of Neurology and Translational Neurosciences, University of Edinburgh and Honorary Consultant Neurologist, NHS Forth Valley

Dr Rebecca Mann BM BS FRCPCH: Consultant Paediatrician, Taunton and Somerset NHS Foundation Trust

Dr Sarah Meredith: Deputy Director, MRC Clinical Trials Unit and Honorary Senior Lecturer, Department of Primary Care and Population Sciences, University College London

Dr Siraj Misbah MBBS (Hons) MSc FRCP FRCPath: Consultant Clinical Immunologist, Lead for Clinical Immunology, Oxford University Hospitals

Professor David G C Owens MD (Hons) FRCP FRCPsych Professor of Clinical Psychiatry, Edinburgh University

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FMedSci David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Associate Executive Pro Vice Chancellor, Director of the Wolfson Centre for Personalised Medicine, Director of the MRC Centre for Drug Safety Science

Professor Shirley Price MSc, PhD, FBTS, FRSB, ERT, FHEA, FRSC, MBPharmacolSoc Professor of Toxicology, Academic Director, Student Progression and Learning Gain

Professor Kevin M G Taylor BPharm PhD MRPharmS Chair of the British Pharmacopoeia Commission and Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London

Professor Angela E Thomas OBE MB BS PhD FRCPE FRCPath FRCPCH (Vice-Chair) Consultant Paediatric Haematologist, Royal Hospital for Sick Children, Edinburgh

Mrs Helen M Ward MSc, BSc (Hons), Senior Fellow HEA, RGN, RCN Nurse Practitioner, PGCEA, PG Cert NMP, Queens Nurse, Advanced Nurse Practitioner

Professor Christopher Weir BSc (Hons) PhD MSc FRSS C.Stat C. Sci Personal Chair in Medical Statistics and Clinical Trials, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh

Dr Martin Wilson MRCP (UK) MPhil (Glasgow), FRCP(Edin) Consultant Physician in Care of the Elderly, Raigmore Hospital, Inverness

Summary minutes

Summary minutes are prepared on the basis that no personal, commercial or otherwise confidential information is disclosed.

See the final summary minutes for CHM and EAGs from 2014 onwards, which you can download.

Yellow Card application form (MS Word Document, 145KB)

Previous minutes can be seen on the MHRA pages on the National Archives

Code of practice for chairmen and members of the commission on human medicines, certain committees and expert advisory groups (PDF, 103KB, 15 pages)

Meeting dates

2017

Jan Feb March April May June July Sept Oct Nov Dec
19/20 16/17 16/17 13/14 11/12 15/16 13/14 7/8 5/6 2/3 7/8

2018

Jan Feb March April May June July Sept Oct Nov Dec
18/19 15/16 15/16 19/20 24/25 21/22 19/20 13/14 11/12 8/9 6/7

Infection EAG

Remit

To advise the Commission on the safety and efficacy of medicines for use in infections including HIV, AIDS and viral hepatitis.

Chair

Professor Jonathan S Friedland MA PhD FRCP FRCPE FRCPI FECCMID FMedSci Deputy Prinicipal, St. George’s University of London: Hon Consultant in Infectious Diseases St George’s University Hospitals NHS Foundation Trust

Members

Professor David Dockrell MB BCh MD FRCPI FRCP (Glas) FACP, Professor of Infection Medicine, University of Edinburgh

Dr Andrew Freedman B.A M.B,B.Chir M.A M.D FRCP FRCP Reader in Infectious Diseases, Cardiff University School of Medicine/ Hon. Consultant Physician, University Hospital of Wales

Dr Richard Gilson MD FRCP Director, Centre for Sexual Health & HIV Research and Head, Research Department of Infection and Population Health, University College London

Dr Richard Hobson MB BS MRCP (UK) FRCPath PhD Consultant Microbiologist and Honorary Senior Lecturer, Harrogate & District NHS Foundation Trust/University of Leeds

Dr Susan Hopkins MB ChB BAO (Hons) BA FRCPI Consultant in Infectious Diseases and Microbiology, Royal Free Hampstead NHS Trust, Healthcare Epidemiologist, Health Protection Agency, Honorary Senior Lecturer, University College London

Dr Katie Jeffery FRCP FRCPath Deputy Director of Infection Prevention and Control, Consultant Microbiologist (Clinical Lead), Oxford University Hospitals NHS Foundation Trust

Professor Martin Lombard MD MSc FRCP (Lond) Consultant Hepatologist & Gastroenterologist, Royal Liverpool University Hospitals NHS Trust

Dr Hermione Lyall BSc Hons MB ChB Hons MD FRCPCH Consultant in Paediatric Infectious Diseases, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London

Professor Kevin Moore BSc MB BS PhD FRCP Professor of Hepatology, Royal Free Hospital, London

Dr Matthias Schmid MD FRCP DTMH Consultant Physician & Honorary Clinical Senior Lecturer, Head of Department of Infection & Tropical Medicine, Royal Victoria Infirmary

Ms Hilary A Shenton CPFA Lay Representative. Retired Secretary to the School of Medicine, University of Sheffield

Cardiovascular, Diabetes, Renal, Respiratory and Allergy EAG

Remit

To advise CHM on the safety and efficacy of medicines for used for the treatment and prevention of cardiovascular, diabetes, renal, respiratory and allergy diseases.

Chair

Dr J Colin Forfar BSc (Hons) MBChB PhD MD MA FRCP FRCP (Edin) Consultant Physician and Cardiologist, John Radcliffe Hospital, Oxford

Members

Dr Amanda Adler MD, PhD, FRCP, Consultant Physician, Diabetes, Addenbrooke’s Hospital, Cambridge University Hospitals

Dr Andrew Carmichael, Consultant Dermatologist, James Cook University Hospital, Middlesbrough

Prof Iolo J Doull DM MRCP FRCPCH Consultant Respiratory Paediatrician, Children’s Hospital for Wales, Cardiff, Deputy Medical Director Welsh Health Specialised Services Committee

Dr John Firth BA BM ChB DM FRCP Consultant Physician and Nephrologist, Addenbrooke’s Hospital, Cambridge

Dr Andrew Grace MB PhD FRCP FACC FESC Consultant Cardiologist, Papworth and Addenbrooke’s Hospitals Cambridge & Research Group Head, Department of Biochemistry, University of Cambridge

Dr Philip W Ind BA Cantab MB BChir MA Cantab FRCP Consultant Physician and Honorary Senior Lecturer in Respiratory Medicine, Imperial School of Medicine, Hammersmith Hospital

Dr Patrick Mark MB CHB (Hons) PhD FRCP Clinical Reader/Honorary Consultant Nephrologist University of Glasgow/Queen Elizabeth University Hospital, Glasgow

Professor Theresa McDonagh BSc (Hons), MB ChB (Hons), MD (Distinction), FRCP, FESC, FHFA Consultant Cardiologist, King’s College Hospital, London & Professor of Heart Failure King’s College, London

Professor Ann Millar MBChB MD FRCP (Vice Chair) Professor in Respiratory Medicine, Bristol University & Honorary Consultant, North Bristol NHS Trust

Dr Hilary Pinnock MB ChB (Hons) MRCGP MD Reader, Asthma UK Centre for Applied Research, Allergy and Respiratory Research Group, University of Edinburgh; General Practitioner, Whitstable Medical Practice

Dr Pallav L Shah MD MBBS FRCP Consultant Physician, Royal Brompton Hospital and Chelsea & Westminster Hospital, Reader in Respiratory Medicine, Imperial College

Dr Caroline Vaughan PhD Lay Representative of MHRA EAGS. Trustee and Director of Contact a Family and FamilyLine

Mr Phil Willan MSc Lay Representative. Member of Pharmacovigilance EAG; Member of the Royal College of Physicians’ (RCP) Patient and Carer Network; Member of the RCP Joint Speciality Committee (JSC) for Renal Medicine, Healthcare Associated Infections Working Group, Specialist Advisory Committee for Renal Medicine, JSC for Allergy and Immunology, Faculty of Forensic and Legal Medicine, Federation CPD Policy Committee and Equality and Diversity Monitoring Committee

Professor Sarah Wild MB BChir MSc PhD FRCPE FFPH, Professor of Epidemiology, Honorary Consultant in Public Health, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh

Meeting dates

2018

Jan March May July Sept Nov
16 12 22 16 11 5

Chemistry, Pharmacy and Standards EAG

Remit

To advise the CHM on the quality in relation to safety and efficacy of medicinal products which are the subject of marketing authorisation applications and to advise on such other matters as are referred to it.

Chair

Professor Kevin M G Taylor BPharm PhD FRPharmS Chair of the British Pharmacopoeia Commission and Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London

Members

Dr Majella Lane BSc PhD Senior Lecturer in Pharmaceutics, UCL School of Pharmacy

Professor Graham Buckton BPharm PhD DSc FRPharmS FRSC Emeritus Professor of Pharmaceutics, UCL School of Pharmacy

Professor Brian J Clark MSc PhD CChem FRSC Professor of Pharmaceutical and Biomedical Analysis, Bradford University

Professor Ruth Duncan PhD Professor Emerita in Cell Biology and Drug Delivery, Cardiff University and Visiting Professor at the University of Greenwich

Mr V’Iain G Fenton-May BPharm MIPharm FRPharmS Pharmaceutical Microbiologist

Professor Geoffrey W Hanlon BSc PhD MRPharmS Emeritus Professor of Pharmaceutical Microbiology, School of Pharmacy & Bio-Molecular Sciences, University of Brighton

Dr Gillian M Hawksworth MBE PhD FFRPS FRPharmS (Hon) DSc Academic Community Pharmacist, Visiting Fellow Lecturer at University of Huddersfield & Past President of the RPSGB

Miss Carol E Knott MRPharmS MBA MIHM Lay Representative. Director of Windcliff Management Ltd

Mr Robert Lowe BPharmS MRPharmS Practising Hospital Pharmacist, NHS Eastern Region

Professor Christopher Marriott PhD DSc Hon DSc FRPharmS CChem FRSC FRSM (Vice Chair) Emeritus Professor of Pharmaceutics, King’s College, London

Professor Yvonne Perrie BSc Hons MRPharmS FAPS FSB PhD Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde.

Ms Hilary A Shenton CPFA Lay Representative. Retired Secretary to the School of Medicine, University of Sheffield

Professor Michael D Threadgill PGCE MA PhD DSc FRSC CChem Professor in Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath

Professor Peter York PhD BSc DSc FRPharmS CChem FRSC FAAPS Emeritus Professor of Pharmaceutics, Bradford University

Meeting dates

2017

Jan Feb March April May June July Sept Oct Oct Dec
17 14 14 11 9 13 11 5 3 31 5

2018

Jan Feb March April May June July Sept Oct Nov Dec
16 13 13 17 22 19 17 11 9 6 4

Clinical Trials, Biologicals and Vaccines EAG

Remit

To advise the CHM on:

  • first time in human (FTIM) studies with new compounds acting (directly or indirectly) via the immune system with a novel target or a novel mechanism of action or having a secondary potential effect on the immune system via a mechanism of action which currently is not well characterised.
  • FTIM studies with novel compounds acting via a possible or likely species specific mechanism
  • Any FTIM studies which are otherwise seen as requiring expert advice
  • Other clinical trials involving classes of compound where MHRA may wish to seek external expert advice or CHM may wish to have oversight
  • Whether a product’s mechanism of action is novel and comes within the scope of the EAG
  • Pre-meeting scientific advice documentation for within scope compounds
  • Other clinical trials where MHRA may wish to seek advice or where there is a difficult risk benefit balance
  • Other clinical trials involving products where a new class safety issue has been identified
  • The quality, safety and efficacy of medicinal products of biological or biotechnological origin including vaccines which are the subject of marketing authorisation applications; and to advise on such other matters as are referred to it

Chair

Professor Angela E Thomas OBE MB BS PhD FRCPE FRCPath FRCPCH Consultant Paediatric Haematologist, Royal Hospital for Sick Children, Edinburgh

Members

Professor Farzin Farzaneh DPhil FRCPath FRSB, Professor of Molecular Medicine, King’s College London, Honorary Consultant in Specialist Medicine, King’s College Hospital NHS Trust

Dr Helen J Lachmann MD FRCP (Vice Chair) Reader and Honorary Consultant in Amyloidosis and Renal Medicine, University College London

Dr Siraj Misbah MBBS (Hons) MSc FRCP FRCPath Consultant Clinical Immunologist, Lead for Clinical Immunology, Oxford University Hospitals

Professor B Kevin Park BSc PhD FMedSci FRCP (Hon) FBTS Director of MRC Centre for Drug Safety Science, Professor of Pharmacology & Head of Institute of Translational Medicine, University of Liverpool

Professor Andrew Pollard PhD FRCPCH Chair of the Joint Committee on Vaccination and Immunisation; Professor of Paediatric Infection and Immunity, University of Oxford

Dr Robin Thorpe PhD FRCPath Retired, Head, Division of Biotherapeutics, National Institute for Biological Standards and Control (NIBSC)

Professor Marc Turner MBBS PhD MBA FRCP FRCPath FHEA Professor of Cellular Therapy; Medical Director Scottish National Blood Transfusion Service (SNBTS)

Mrs Madeleine Wang BA (Hons) Lay Representative. Patient Advocate

Professor Christopher Weir BSc (Hons) PhD MSc FRSS C.Stat C. Sci Personal Chair in Medical Statistics and Clinical Trials, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh

Meeting dates

2017

Jan Feb March April May June July Sept Oct Oct Dec
16 13 13 10 8 12 10 4 2 30 4

2018

Jan Feb March April May June July Sept Oct Nov Dec
15 12 12 16 21 18 16 10 8 5 3

Gastroenterology, Rheumatology, Immunology and Dermatology EAG

Remit

To advise the CHM on the safety and efficacy of medicines for use in gastroenterological, rheumatological, immunological, and dermatological diseases.

Chair

Professor Anthony G Wilson MB BCH BAO DCH PhD FRCP Professor of Rheumatology, Medical School, University of Sheffield

Members

Dr Michael Ardern-Jones BSc MBBS DPhil FRCP Associate Professor, University of Southampton and Consultant Dermatologist

Dr Ian Barrison BSc MB FRCP FEBGH President European Board of Gastroenterology and Hepatology; Associate Dean, Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire

Mr David Chandler Lay Representative. Chief Executive, Psoriasis and Psoriatic Arthritis Alliance, Hertfordshire

Professor Kevin Moore BSc MB BS PhD FRCP Professor of Hepatology, Royal Free Hospital, London

Dr Frances Williams BSc MBBS MRCP PhD CCST FRCP (Edin) Reader in Genetic Epidemiology and Hon Consultant Rheumatologist, King’s College London

Meeting dates

Medicines for Women’s Health EAG

Remit

To advise the CHM on the safety and efficacy of medicines related to endocrinology and women’s reproductive health from menarche to menopause and conditions related to the menopause, such as osteoporosis. The medicines covered will include medicines for contraception, emergency contraception and termination of pregnancy; medicines for infertility and assisted conception; hormone replacement therapy (HRT) and non-hormonal treatments for osteoporosis.

Chair

Dr Ailsa Gebbie MB ChB FRCOG FRCPE FFSRH Consultant Gynaecologist and Deputy Director, Chalmers Centre, Edinburgh

Members

Professor Philip Hannaford MB ChB DRCOG DCH MD FRCGP FFSRH FFPH Professor of Epidemiology, University of Aberdeen

Ms Linda Pepper BA MA (Education) Independent Consultant: patient and public involvement in healthcare

Professor Siobhan Quenby MBBS BSc MD FRCOG Professor of Obstetrics, Warwick University

Dr Clare Spencer MA MB BCHIR DM MRCOG MRCGP DFFPRHC GP Partner

Professor Jonathan H Tobias BA (Cantab) MBBS PhD (London) FRCP MD (London) Professor of Rheumatology, University of Bristol, and Honorary Consultant Rheumatologist, North Bristol Trust

Mrs Claire Bellone RGN MSc NMP, Clinical Nurse Specialist, Chelsea & Westminster Hospital, London

Ms Julia Louise Tassano-Smith, Nurse Consultant, Department of Sexual Health, Royal Berkshire NHS Foundation Trust

Meeting dates

Neurology, Pain and Psychiatry EAG

Remit

To advise the CHM on the safety and efficacy of medicines for use in neurological conditions, pain management and psychiatric conditions.

Chair

Professor David G C Owens MD (Hons) FRCP FRCPsych Professor of Clinical Psychiatry, Edinburgh University

Members

Professor Thomas R. E. Barnes MD FRCPsych DSc Professor of Clinical Psychiatry, Imperial College London

Professor Naomi Fineberg BA Hons MB BS MA MRCPsych Consultant in General Adult Psychiatry, Hertfordshire Partnership NHS

Dr David Hunt MBMS MRCP PhD Honorary Consultant Neurologist/ Wellcome Trust Clinician Scientist, Anne Rawling Regenerative Neurology Clinic, University of Edinburgh

Professor Malcolm R Macleod BSc MBChB MRCP PhD FRCP (Edin) (Vice Chair) Professor of Neurology and Translational Neurosciences, University of Edinburgh and Honorary Consultant Neurologist, NHS Forth Valley

Professor John T O’Brien BA MA BMBCh DM FRCPsych Professor of Old Age Psychiatry, University of Cambridge

Dr Waqar Rashid MBBS BSc MRCP(UK) PhD Consultant and Honorary Clinical Senior Lecturer in Neurology, Brighton and Sussex University Hospitals NHS Trust, member of the Multiple Sclerosis Society

Dr Fergus Rugg-Gunn MB BS MRCP PhD Consultant Neurologist, National Hospital for Neurology and Neurosurgery, Queen Square, London

Dr Aditya Sharma MBBS MD MRCPsych PhD Consultant (Northumberland Tyne and Wear NHS Foundation Trust) & Honorary Clinical Senior Lecturer (Newcastle University) in Child and Adolescent Psychiatry at Adolescent Bipolar Service

Dr Catherine F Stannard MB ChB FRCA FFPMRCA Consultant in Complex Pain/Pain Transformation Programme Clinical Lead, NHS Gloucestershire CCG

Professor Christopher Weir BSc (Hons) PhD MSc FRSS C.Stat C. Sci Personal Chair in Medical Statistics and Clinical Trials, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh

Meeting dates

Oncology and Haematology EAG

Remit

To advise the CHM on the safety, quality and efficacy of medicines used in the treatment of malignant disease or blood disorders.

Chair

Professor Martin Gore CBE MBBS PhD FRCP Medical Director and Consultant Medical Oncologist, The Royal Marsden NHS Foundation Trust and Professor of Cancer Medicine, Institute of Cancer Research

Members

Professor David Bowen MA MB Bchir MD MRCP FRCPath,Consultant Haematologist, Leeds Teaching Hospitals and Honorary Professor of Myeloid Leukaemia Studies, University of Leeds

Professor Stephen Devereux PhD FRCP FRCPath Consultant Haematologist, Kings College Hospital

Dr Hugo Ford MA MB BChir MD FRCP Director of Cancer Services, Cambridge University Hospitals

Dr Chris Gallagher BSc PhD FRCP Consultant Medical Oncologist, St Bartholomew’s Hospital, Barts and the London NHS Trust

Dr Geoff Shenton Consultant & Associate Clinical Lecturer in Paediatric and Adolescent Haematology & BMT, Great North Children’s Hospital, Newcastle upon Tyne

Professor Angela E Thomas OBE MB BS PhD FRCPE FRCPath FRCPCH (Vice-Chair) Consultant Paediatric Haematologist, Royal Hospital for Sick Children, Edinburgh

Invited expert

Professor A Hilary Calvert MB BChir MSc MD FRCP FMedSci Director of Cancer Drug Discovery and Development, UCL Cancer Institute

Paediatric Medicines EAG

The remit of the EAG is to advise the CHM on the safety, quality and efficacy of medicines for paediatric use, including all matters relating to the implementation of the EU Paediatric Regulation.

Chair

Dr Rebecca Mann BMBS FRCPCH Consultant Paediatrician, Taunton and Somerset NHS Foundation Trust

Members

Dr Eileen M Baildam MB ChB DRCOG DCH RCP FRCP FRCPCH Consultant Paediatric Rheumatologist and Honorary Senior Lecturer, Alder Hey Foundation NHS Trust and University of Liverpool

Dr Helen Burdett MB ChB MRCP FRCA Consultant Anaesthetist, Tunbridge Wells Hospital

Professor J Helen Cross MB ChB PhD FRCP FRCPCH, the Prince of Wales’s Chair of Childhood Epilepsy, Deputy Head of Developmental Neurosciences Programme, UCL Institute of Child Health

Professor Steven Cunningham MBChB PhD FRCPCH (Vice Chair) Consultant and Honorary Professor in Paediatric Respiratory Medicine, NHS Lothian Royal Hospital for Sick Children and University of Edinburgh

Dr Meriel Jenney MBChB MRCP MD FRCPCH Consultant Paediatric Oncologist/Assistant Medical Director (Cancer Services), Children’s Hospital for Wales

Dr Caroline Jones MB ChB FRCPCH MD, Consultant Paediatric Nephrologist, Alder Hey Children’s NHS Foundation Trust

Professor Nigel Klein BSc MBBS MRCP PhD FRCPCH Consultant, Great Ormond Street Hospital for Children NHS Trust; Professor of Infectious Diseases and Microbiology, Institute of Child Health, UCL

Dr Rubin Minhas MB ChB MBA GP Principal

Professor Marie-Louise Newell MB MSc PhD FMedSci Professor of Global Health, Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton

Professor Anthony Nunn BPharm FRPharmS Hon FRCPCH Honorary Fellow, Department of Women’s and Children’s Health, University of Liverpool; Industry Professor, School of Pharmacy and Biomedical Sciences, Liverpool John Moores University, Alder Hey Children’s Hospital, Liverpool

Ms Sara Payne BA CPE LPC Lay Representative. Solicitor

Professor Heather M Wallace PhD FRCPath FRSC FSB FBPharmacolS FBTS European Registered Toxicologist Professor of Biochemical Pharmacology and Toxicology, Division of Applied Medicine, University of Aberdeen

Dr Mark Whiting BNursing MSc PhD Consultant Nurse, Children’s Community and Specialist Nursing, Peace Children’s Centre, Hertfordshire Community NHS Trust

Dr Morris Zwi MB BCh FRCPsych Consultant Child & Adolescent Psychiatrist & Clinical Lead, Child & Adolescent Mental Health Services, Whittington Health, Clinical Lead for Islington Child & Adolescent Mental Health Services

Meeting dates

2017

Jan Feb March April May June July Aug Sept Oct Nov
10 8 7 6 3 6 4 2/29 26 25 30

2018

Jan Feb March April May June July Aug Sept Oct Nov
10 6 6 11 16 12 10 9 4 3/30 29

Patient and Public Engagement EAG

The remit of the EAG will be to advise the Commission on Human Medicines (CHM) on:

  • the development of effective communications for patients, the public and carers to help them make informed choices about medicines and to use medicines safely
  • how to improve communication between patients and health professionals and between the MHRA and the public on the safe use of medicines
  • ways to promote the availability and accessibility of high quality information about individual medicines available in the UK
  • ways to encourage reporting of adverse drug reactions (ADRs) by patients and the public - recognising the importance of the patient experience, to advise on building links between patient concerns as experienced in direct ADR reports and the information provided to patients
  • facilitating targeted patient involvement on relevant regulatory issues, where patient/public involvement has not otherwise been achieved by working with specific patient organisations
  • providing a patient perspective on strategic issues such as the upcoming European legislation on Patient Information

Chair Pro Tem

Mr Phil Willan MSc (Vice-Chair) Lay Representative. Member of the Royal College of Physicians (RCP) Patient and Carer Network; Member of the RCP Joint Speciality Committee (JSC) for Renal Medicine, Healthcare Associated Infections Working Group, Specialist Advisory Committee for Renal Medicine, JSC for Allergy and Immunology, Faculty of Forensic and Legal Medicine, Federation CPD Policy Committee and Equality and Diversity Monitoring Committee

Members

Ms Hellen Adom BA MA Lay Member. Outreach Assistant, NHS Sickle Cell & Thalassaemia Screening Programme, London

Mr David Chandler Lay Member. Chief Executive, Psoriasis and Psoriatic Arthritis Alliance, Hertfordshire

Mr John Chapman LL.B (Lon) Lay Member. Patient/Carer Member

Mrs Joyce Epstein Lay Member. Former Director of the Foundation for the Study of Infant Deaths (FSID)

Dr Nicola Jane Gray PhD MRPharmS FHEA FSAHM (US) Lay Member. Independent Pharmacist Researcher, Manchester

Ms Amanda Hoey Lay Member. Director, ConsumerHealth Consulting Ltd. Independent Health Policy and Strategy Consultant

Mrs Farrah Pradhan Lay Member. Invited Reviews Coordinator at the Royal College of Obstetricians and Gynaecologists

Mrs June Rogers MBE RN RSCN BA (Hons) MSc Lay Member. PromoCon Paediatric Advisor, Disabled Living

Dr Bella Starling PhD BSc Hons Dip Lay Member. Director of Public Programmes, Nowgen, a Centre for Genetics in Healthcare

Mr Paddy Storrie MA (Oxon) NPQH Lay Member. Deputy Headmaster, St. George’s School, Hertfordshire and Lay Member, N.I.C.E Technology Appraisals Committee

External experts

Mrs Anne Joshua BPharm (Hons) MSc Pharm Dip MRPharmS NHS 111 Pharmacy Lead, NHS England

Professor Angus Mackay OBE MA PhD (Cantab) MB ChB BSc (Pharmacol) FRCP (Edin) FRCPsych TPsych Professor of Psychological Medicine, University of Glasgow

Professor D K Theo Raynor BPharm (Hons) PhD MRPharmS Professor of Pharmacy Practice, University of Leeds

Pharmacovigilance EAG

PEAG now review applications for access to Type II Yellow Card data, the completed application form should be emailed directly to pharmacovigilanceservice@mhra.gov.uk

Yellow Card application form (MS Word Document, 145KB)

Remit

To advise the CHM on the following in relation to human medicines including herbal products:

  • the public health importance of potential new signals
  • the confirmation and quantification of risks identified
  • appropriate risk minimisation measures including communications
  • design and progress of pharmacovigilance plans
  • methodologies for pharmacovigilance.

Chair

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FMedSci David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Associate Executive Pro Vice Chancellor, Director of the Wolfson Centre for Personalised Medicine, Director of the MRC Centre for Drug Safety Science

Members

Professor Jamie Coleman MD MA (Med Ed) FRCP FBPhS Professor in Medical Education / Consultant Clinical Pharmacologist, University of Birmingham

Professor William Dixon MRCP PhD MRC Clinician Scientist and Honorary Consultant Rheumatologist, The University of Manchester

Dr Ian J Douglas BSc MSc PhD Senior Lecturer in Pharmacoepidemiology, London School of Hygiene & Tropical Medicine

Professor Simon R J Maxwell MD PhD FRCP FRCPE FBPharmacolS FHEA Professor of Student Learning/Clinical Pharmacology, Western General Hospital, Edinburgh & University of Edinburgh

Dr Karen Miller BSc MBBS DRCOG DCH DFFP FRCGP GP Partner, Adelaide Medical Centre, London

Dr Rupert Payne MB ChB MRCP PhD MRCGP FRCP, Consultant Senior Lecturer in Primary Care, University of Bristol

Dr Nicholas J Plant BSc PhD Reader in Molecular Toxicology, University of Surrey

Ms Christine Randall BPharm MRPharmS, Assistant Director, North West Medicines Information Centre

Dr Ruben Thanacoody MD FRCP FRCP (Edin) Consultant Physician, Royal Victoria Infirmary; Honorary Clinical Senior Lecturer, Institute of Cellular Medicine, Newcastle University

Mr Phil Willan MSc Lay Representative. Member of the Royal College of Physicians (RCP) Patient and Carer Network; Member of the RCP Joint Speciality Committee (JSC) for Renal Medicine, Healthcare Associated Infections Working Group, Specialist Advisory Committee for Renal Medicine, JSC for Allergy and Immunology, Faculty of Forensic and Legal Medicine, Federation CPD Policy Committee and Equality and Diversity Monitoring Committee.

Dr Caroline Vaughan PhD Lay Representative of MHRA EAGS. Governor of the Surrey and Sussex Healthcare NHS Trust

Ms Susan Hunneyball BSc (Hons) Lay Member

Meeting dates

2017

Jan Feb March April May June Aug Sept Oct Nov
4 1 1/29 26 31 28 23 20 18 22

2018

Jan Feb April May June Aug Sept Oct Nov
3/31 28 4 9 6/27 29 26 24 21

Type II Yellow Card data

PEAG now review applications for access to Type II Yellow Card data, the completed application form should be emailed directly to pharmacovigilanceservice@mhra.gov.uk

Yellow Card application form (MS Word Document, 145KB)

Sodium Valproate Expert Working Group

Terms of reference of the Sodium Valproate expert Working Group

  • To review the current risk minimisation in place and possible reasons for lack of effectiveness.
  • To consider further regulatory measures required to minimize the risk of valproate use in pregnancy including, but not limited to, a contraindication for use in pregnancy in girls and women without effective contraception and a formal Pregnancy Prevention Program.
  • To consider other measures required across the healthcare system to ensure compliance with regulatory position in clinical practice (e.g. shared care agreements, registries.

Chair

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS FMedSci David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Associate Executive Pro Vice Chancellor, Director of the Wolfson Centre for Personalised Medicine, Director of the MRC Centre for Drug Safety Science

Members

Professor J Helen Cross OBE MB ChB PhD FRCP FRCPCH The Prince of Wales’s Chair of Childhood Epilepsy, Deputy Head of Developmental Neurosciences Programme, UCL Institute of Child Health

Dr Martin Duerden B Med Sci, MB BS, DRCOG, Dip Ther, DPH, FRCGP Member of National Stakeholder Platform, Honorary Senior Research Fellow, Centre for Health Economics and Medicines Evaluation, Bangor University

Professor Jayne Lawrence Professor of Biophysical Pharmaceutics, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester University and Visiting Professor of Biophysical Pharmaceutics, Institute of Pharmaceutical Science, King’s College London

Dr John Paul Leach Honorary Associate Clinical Professor, School of Medicine, Dentistry and Nursing, University of Glasgow, Elected Member of the Association of British Neurologists (ABN)

Dr Janine Lynch BHSCT Psychiatrist, Belfast Health & Social Care Trust

Dr Rebecca Mann BMBS FRCPCH Consultant Paediatrician, Taunton and Somerset NHS Foundation Trust

Dr Karen Miller BSc MBBS DRCOG DCH DFFP FRCGP GP Partner, Adelaide Medical Centre, London

Professor Catherine Nelson-Piercy MBBSMA, FRCP, FRCOG Professor of Obstetric Medicine and Consultant Obstetric Physician, Guy’s & St Thomas’ Foundation Trust

Professor David G C Owens MD (Hons) FRCP FRCPsych Professor of Clinical Psychiatry, Edinburgh University

Ms Clare Pelham Chief Executive of the Epilepsy Society

Dr Fergus Rugg-Gunn MB BS MRCP PhD Consultant Neurologist, National Hospital for Neurology and Neurosurgery, Queen Square, London

Ms Laura Russell Senior Policy and Public Affairs Officer Family Planning Association

Professor Philip Smith Consultant Neurologist, Cardiff School of Medicine and former President of the Association of British Neurologists (ABN)

Mrs Madeleine Wang BA (Hons) Lay Representative. Patient Advocate

Invited expert

Professor Thomas R. E. Barnes MD FRCPsych DSc Professor of Clinical Psychiatry, Imperial College London

Contents