National Vaccine Evaluation Consortium

The National Vaccine Evaluation Consortium (NVEC) conducted a large number of clinical trials over several decades, ceasing existence at the end of 2018. Details of these trials can be found in the 'past studies' section below.

If you have a question or need advice in relation to these studies, please contact Dr Elizabeth Coates in the Public Health England (PHE) Research and Development (R&D) office elizabeth.coates@phe.gov.uk

Role

The National Vaccine Evaluation Consortium (NVEC):

  • evaluated new vaccines and vaccination schedules to inform decisions about vaccinations given by the NHS
  • provided this information to the Department of Health using data from clinical trials in adults, children and babies
  • assisted the Department of Health in developing the UK national immunisation schedule

In partnership with universities and NHS researchers, NVEC members were experts in their field: doctors, laboratory scientists, epidemiologists, nurses, statisticians and data managers. Some partners were involved in all studies, some in particular pieces of work only.

NVEC coordinated most of its clinical trials at PHE through the Immunisation, Hepatitis and Blood Safety Health Protection Service. The trials took place at PHE clinical hubs in Gloucestershire and Hertfordshire.

Past clinical trials

NVEC trials assess the likely effect on people of a new vaccine when it is introduced. Find out more about clinical trials on NHS Choices.

Flushed

Information leaflet for children aged 6 to 13 years: flushed (PDF, 208 KB, 2 pages) Information leaflet for parents and carers: flushed (PDF, 316 KB, 11 pages)

PRIME follow up

PRIME follow up information leaflet (PDF, 160 KB, 4 pages)

HPV follow up

HPV follow up information leaflet (PDF, 159 KB, 4 pages)

Find out about the HPV follow up.

Multiboost

Information leaflet for participants aged 16 and above: Multiboost study (PDF, 293 KB, 8 pages) Information leaflet for participants aged under 16: Multiboost study (PDF, 145 KB, 2 pages) Parents and guardians information leaflet for those under 16: Multiboost study (PDF, 274 KB, 8 pages)

Find out about Multiboost vaccine trial.

Sched3

Parent information leaflet (PDF, 333 KB, 7 pages)

Hepatitis B vaccination in infants (Infanrix)

Infanrix.

iMAP2

iMAP2.

Pneumococci in the nose (PIN)

Participant information leaflet (PDF, 394 KB, 4 pages) Information leaflet for under 5 year olds (PDF, 297 KB, 1 page) Information leaflet for 5-10 year olds (PDF, 380 KB, 1 page) Information leaflet for 11-16 year olds (PDF, 360 KB, 2 pages) Information leaflet for 16-18 year olds (PDF, 398 KB, 4 pages)

LAIV immuno

Parent information leaflet (PDF, 204 KB, 8 pages) Information leaflet for 5-6 year olds (PDF, 314 KB, 1 page) Information leaflet for 7-10 year olds (PDF, 159 KB, 1 page)

For more information about past clinical trials, see The National Archives.

Contact details

elizabeth.coates@phe.gov.uk