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Evaluate a patient’s individual factors for benefits and risks before initiating treatment with denosumab 60mg, particularly in those with previous vertebral fracture. Patients should not stop denosumab without specialist review.
Serious and life-threatening hypercalcaemia has been reported with denosumab 60mg (Prolia) in children and adolescents in clinical trials for osteogenesis imperfecta and during off-label use. Denosumab 60mg (Prolia) is authorised for use in adults with osteoporosis and other bone loss...
This monoclonal antibody – the second to be authorised by the Medicines and Healthcare products Regulatory Agency – is for people with mild to moderate COVID-19 who are at high risk of developing severe disease.
A pharmaceutical company supported by Innovate UK is leading the world in the search for vital new antibiotics to treat resistant bacteria.
The public has until 5 March to respond to the consultation on the potential reclassification of desogestrel to a pharmacy medicine.
Risk of thrombosis and haemorrhage in patients with prosthetic heart valve(s) requiring anti-coagulant treatment.
Denosumab is associated with a risk of osteonecrosis of the jaw, osteonecrosis of the external auditory canal has also been reported with denosumab.
Rare cases of atypical femoral fracture with long-term use.
Employment Tribunal decision.
Canadian Ambassador Jocelyn Kinnear gives a statement on behalf of four OSCE participating States on prosecution and imprisonment of Vladimir Kara-Murza.
Deputy Ambassador Brown says that Russia's illegal war has had an impact on human rights and fundamental freedoms in Ukraine, Russia and across the OSCE region.
Regular safety information for healthcare professionals
Slovak Ambassador to the OSCE, Peter Mišik, highlights that Russia has systematically clamped down on its own people over the last two decades.
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