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Non-tech summaries 2016: projects on oncology

Projects granted during 2016 that have a primary purpose of basic research, oncology.

From:
Home Office
Published
22 December 2017

Documents

Non-technical summaries: projects granted in 2016, volume 1

PDF, 538 KB, 58 pages

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of basic research, oncology.

The following projects were granted:

  • renal cell carcinoma pathogenesis (renal cancer, genetics, carcinogenesis)

  • centrosomes in development and cancer (centrosome, chromosome heritance, cilia disease, microcephaly, cancer)

  • preclinical models of brain tumours (brain tumours, brain metastases, glioma)

  • production and supply of biological products (tissues, monoclonal / polyclonal antibodies, macrophages)

  • role of cell cycle regulators in gene regulation (cell division, gene regulation, cells)

  • cancer and the micro-environment (cancer, leukaemia, myeloma, micro-environment)

  • epithelial stem cell plasticity; relevance to cancer (epithelium, plasticity, stem cells, progenitor cells, cancer)

  • investigating ubiquitin ligases in disease. (cancer, neurodegenerative disease, protein degradation)

  • understanding mechanisms that regulate tumourigenesis and metastasis (mouse, cancer, metastasis, immune system)

  • cell motility and tumour progression (cancer, metastasis, embryonic development)

  • studying the host response to tumour and metestasis (cancer – host interaction)

  • analysis of skin carcinogenesis in transgenic mice (carcinogenesis, skin, transgenic, mechanism)

  • image studies of cancer (tumour, imaging, therapy)

  • metabolism as a novel target for cancer therapy (cancer, metabolism)

  • targeting the mechanistic drivers of lung tumour progression (tumour progression, therapy, lung cancer)

Published 22 December 2017

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