Assessing anti-T. cruzi candidates in vitro for sterile cidality

This research is an output from the Drugs for Neglected Diseases (DNDi) initiative

From:
Department for International Development
Published
1 December 2016
Document Type:
Journal Article
Theme:
Health
Authors:
Cal, M, loset, J.R., Fugi, M, Masera, P, Kaiser, M

Abstract

It seems to be important for new drug candidates for Chagas disease to totally clear the T. cruzi infection (sterile cure), thus ensuring long-term beneficial effects for patients in the chronic indeterminate stage avoiding relapse. The authors have adapted an in vitro system to predict the ability of a compound to deliver sterile cure.

This research was primarily funded by the Drugs for Neglected Diseases (DNDi) initiative.

Citation

Cal M, Ioset JR, Fügi M, Mäsera P, Kaiser M. (2016). Assessing anti-T. cruzi candidates in vitro for sterile cidality. International Journal for Parasitology: Drugs and Drug Resistance Volume 6, Issue 3, December 2016, Pages 165-170 https://doi.org/10.1016/j.ijpddr.2016.08.003

Assessing anti-T. cruzi candidates in vitro for sterile cidality

Published 1 December 2016
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