We use some essential cookies to make this website work.
We’d like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services.
We also use cookies set by other sites to help us deliver content from their services.
You have accepted additional cookies. You can change your cookie settings at any time.
You have rejected additional cookies. You can change your cookie settings at any time.
Departments, agencies and public bodies
News stories, speeches, letters and notices
Detailed guidance, regulations and rules
Reports, analysis and official statistics
Consultations and strategy
Data, Freedom of Information releases and corporate reports
Interrupt treatment if posterior reversible encephalopathy syndrome (PRES) is confirmed and resume treatment only once the event is resolved and the benefit of continued treatment outweighs the risk of PRES.
Prescribers should consider reducing the dose of ponatinib to 15 mg a day for patients with chronic phase chronic myeloid leukaemia (CP-CML) who have achieved a major cytogenetic response.
Available evidence shows that the risk of blood vessel blockage with ponatinib is likely to be dose-dependent, however the data are insufficient to recommend reducing the ponatinib dose.
Patients should be tested for hepatitis B virus before starting treatment with BCR-ABL tyrosine kinase inhibitors.
In April 2016, letters were sent regarding canagliflozin (Invokana▼, Vokanamet▼), BCR-ABL tyrosine kinase inhibitors, pomalidomide (Imnovid▼), and retigabine (Trobalt)
Employment Appeal Tribunal Judgment of Judge Auerbach on 28 March 2024.
New legislation will provide extra protections for victims' counselling notes during criminal investigations.
Register for Self Assessment and Class 2 National Insurance when you've joined a partnership using form SA401.
Product Recall for JOrange Hand-Tie Life Jacket DTS-95-I sold via Amazon presenting a serious risk of drowning.
Check the tariff classification for flavour pods.
Product Recall for Vincenza Jewellery Pave Zircon Initial Cord Bracelet presenting a serious chemical risk.
The process for applicants applying for a Paediatric Investigation Plan (PIP) modification or waiver.
Advice and guidance on the health needs of migrant patients from Jordan for healthcare practitioners.
Check the tariff classification for a vlogging kit with ring light made of plastics.
Advice and guidance on the health needs of migrant patients from Benin for healthcare practitioners.
Advice and guidance on the health needs of migrant patients from Paraguay for healthcare practitioners.
Product Recall for Anti-Fall safety belt/harness for outdoor activities sold via AliExpress presenting a serious risk of injuries.
Check the tariff classification for impregnated glass fibre weave articles.
This series collates all documents relating to Rotavirus vaccination programme for infants
Don’t include personal or financial information like your National Insurance number or credit card details.
To help us improve GOV.UK, we’d like to know more about your visit today. We’ll send you a link to a feedback form. It will take only 2 minutes to fill in. Don’t worry we won’t send you spam or share your email address with anyone.