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Interrupt treatment if posterior reversible encephalopathy syndrome (PRES) is confirmed and resume treatment only once the event is resolved and the benefit of continued treatment outweighs the risk of PRES.
Prescribers should consider reducing the dose of ponatinib to 15 mg a day for patients with chronic phase chronic myeloid leukaemia (CP-CML) who have achieved a major cytogenetic response.
Available evidence shows that the risk of blood vessel blockage with ponatinib is likely to be dose-dependent, however the data are insufficient to recommend reducing the ponatinib dose.
Patients should be tested for hepatitis B virus before starting treatment with BCR-ABL tyrosine kinase inhibitors.
A new pathway supporting innovative approaches to the safe, timely and efficient development of medicines to improve patient access.
The process for applicants applying for a Paediatric Investigation Plan (PIP) modification or waiver.
Product Recall for Vincenza Jewellery Pave Zircon Initial Cord Bracelet presenting a serious chemical risk.
The Intellectual Property Office offers different methods of accelerating the processing of your patent application.
Product Recall for JOrange Hand-Tie Life Jacket DTS-95-I sold via Amazon presenting a serious risk of drowning.
Product Recall for ByKallevig Evdano Upholstered dining chairs presenting a medium risk of fire.
Advice and guidance on the health needs of migrant patients from Benin for healthcare practitioners.
In April 2016, letters were sent regarding canagliflozin (Invokana▼, Vokanamet▼), BCR-ABL tyrosine kinase inhibitors, pomalidomide (Imnovid▼), and retigabine (Trobalt)
This series collates all documents relating to Rotavirus vaccination programme for infants
Information for healthcare professionals and the public about the adapted Spikevax XBB.1.5 vaccine
Information on taking, submitting and processing samples which potentially contain monkeypox virus.
Advice and guidance on the health needs of migrant patients from Paraguay for healthcare practitioners.
Public health advice for prisons and other prescribed places of detention.
Advice and guidance on the health needs of migrant patients from Jordan for healthcare practitioners.
Guidance and resources to resolve common fingermark visualisation queries and help forensic laboratories achieve and maintain ISO 17025.
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