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The monitoring requirements and discontinuation criteria for dimethyl fumarate (Tecfidera) have been strengthened following a small number of reports of progressive multifocal leukoencephalopathy (PML) in patients with mild lymphopenia. Continue to monitor lymphocyte counts and advise patients to seek urgent...
Cases of progressive multifocal leukoencephalopathy have been reported in patients taking dimethyl fumarate for multiple sclerosis, who all had prolonged lymphopenia.
Check full blood counts before prescribing dimethyl fumarate and then every 6 to 12 months. Stop treatment immediately if you suspect progressive multifocal leukoencephalopathy.
Understand the challenges and considerations around using GraphQL such as security, versioning, caching, tooling and team skills.
Funding for the development of innovative ideas that promote renewable energy.
This series brings together all documents relating to September 2012 DFID progress updates on implementing ICAI recommendations
Check the tariff classification for articles made of cermet.
BDUK has awarded broadband provider FullFibre a Project Gigabit contract to provide around 7,900 premises across West Herefordshire and Forest of Dean with access to gigabit-capable broadband.
This series brings together all documents relating to March 2013 DFID progress updates on implementing ICAI recommendations
The government technology and service design standards that GovTech Catalyst funded challenges must meet.
News stories and speeches about the GovTech Catalyst.
This series brings together all documents relating to Defra's Permanent Secretary’s meetings with external organisations
Review looking at the future of financial technologies up to 2025.
This is a list of the RPC's Register of Interests for 2022
Decision for applicant Xerox Corporation and Xerox Limited registration number 14948448, applicant successful.
Explainer for the pharmaceutical industry on Renewal requirements mitigations to bridge the gap between the implementation of the EU Regulation on veterinary medicines and the revised Veterinary Medicines Regulations as they have an effect in Great Britain (GB VMR).
Harakat is a grant facility that aims to create a better environment for business in Afghanistan.
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