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The monitoring requirements and discontinuation criteria for dimethyl fumarate (Tecfidera) have been strengthened following a small number of reports of progressive multifocal leukoencephalopathy (PML) in patients with mild lymphopenia. Continue to monitor lymphocyte counts and advise patients to seek urgent...
Cases of progressive multifocal leukoencephalopathy have been reported in patients taking dimethyl fumarate for multiple sclerosis, who all had prolonged lymphopenia.
Check full blood counts before prescribing dimethyl fumarate and then every 6 to 12 months. Stop treatment immediately if you suspect progressive multifocal leukoencephalopathy.
A summary of letters and drug alerts recently sent to healthcare professionals.
The Government Property Agency (GPA) has appointed Gleeds as a strategic partner to provide professional services for its Capital Programmes.
In November, letters were sent regarding thalidomide, mycophenolate mofetil, nicorandil, InductOs, and dimethyl fumarate
Employment Appeal Tribunal Judgment of Judge Tayler on 12 April 2024.
An overview of the legal requirements for children’s medicines that Marketing Authorisation Holders (MAHs) need to abide by.
Product Safety Report for TUMAKOU High Frequency Beauty Machine presenting a high risk of electric shock.
Review looking at the future of financial technologies up to 2025.
This series brings together all documents relating to Defra's Permanent Secretary’s meetings with external organisations
BDUK has awarded broadband provider FullFibre a Project Gigabit contract to provide around 7,900 premises across West Herefordshire and Forest of Dean with access to gigabit-capable broadband.
Details about our Private Finance team, our work and the history of private finance for social housing.
An overview of the CSSF, including 2022 to 2023 highlights, and its achievements before the UK Integrated Security Fund (ISF) replaced it.
Find out which investments qualify for Innovative Finance Individuals Savings Accounts (ISAs).
Use a separate statement of objection form for each Japanese GI product name you object to.
The ETL (or Energy Technology Product List, ETPL) is a government list of energy-efficient plant and machinery.
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