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How to notify the MHRA of your intention to carry out a clinical investigation for medical devices.
Advice for medical professionals to follow when assessing drivers with neurological disorders.
Information about what to do if you receive a warning or advisory letter from the CMA.
We have strengthened the safe use of isotretinoin through the introduction of additional oversight of the initiation of isotretinoin in patients under 18 years and through improved assessment and monitoring of mental health and sexual function issues. We ask healthcare...
The alerting system provides an early warning when adverse temperatures are likely to impact on the health and wellbeing of the population.
How to manage cases of suspected measles: what patient details to take, who to notify and assessing risk of disease spreading in close contacts.
The review of the safety of isotretinoin has concluded.
A retrospective hospital-based, cross-sectional study carried out between 2016 to 2017
Information for manufacturers of medical devices about reporting adverse incidents and field safety corrective actions to the MHRA.
Advice for medical professionals for assessing fitness to drive.
Advice for medical professionals to use when assessing drivers with cardiovascular disorders.
Batch recall alert for human eye gels that may be prescribed by vets and used under the cascade.
TACO is one of the most common causes of transfusion-related deaths in the UK and cases have increased substantially in recent years. Identifying risk factors for TACO prior to transfusion allows initiation of appropriate mitigating measures.
How to submit a cosmetic product notification to the Office for Product Safety and Standards (OPSS).
Change your protocol, update your authorisation, report safety issues, submit safety updates and complete your end-of-trial study report.
This guidance sets out the warning statements which should appear on the label and/or in the leaflet of certain medicines.
The MHRA is asking organisations to put a plan in place to implement new regulatory measures for sodium valproate, valproic acid and valproate semisodium (valproate). This follows a comprehensive review of safety data, advice from the Commission on Human Medicines...
NSCWIP is the UK’s primary independent group that offers advice to the Cabinet Office on best practice for warning and informing the public during an emergency or major incident. It is made up of professionals, practitioners and academics with a...
This alert highlights the Adult Renal Association Clinical Practice Guidelines (2020) recommendation on calcium gluconate use to support organisations to update local policies and guidelines for the treatment of severe hyperkalaemia in adults.
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